Bringing It All Together: Bedside to Bench and Back Again.

From bedside to bench and back again.

Behavioral disruption of memory reconsolidation: From bench to bedside and back again.

During the postretrieval reconsolidation "window", memories can be disrupted, strengthened, or updated using various pharmacological and behavioral manipulations. Behavioral manipulations are more ecologically valid, thus allowing better understating of memory modification under natural conditions, but they can also be less potent compared to pharmacological interventions. In this review we pre...

The 'action-research' philosophy: from bedside to bench, to bedside again.

Submitted by Emmanuel Lemoine on Wed, 04/22/2015 16:44 Titre The ‘Action-Research’ philosophy: from bedside to bench, to bedside again Type de publication Article de revue Auteur Beauchet, Olivier [1], Fantino, Bruno [2], Annweiler, Cédric [3] Editeur Wiley Type Article scientifique dans une revue à comité de lecture Année 2012 Langue Anglais Date 2012 Numéro 5 Pagination 517-517 Volume 66 Titr...

From bench to bedside: bringing immunotherapy into the clinic.

GPIIb/IIIa inhibitors: from bench to bedside and back to bench again.

From the discovery of the platelet glycoprotein (GP) IIb/IIIa and identification of its central role in haemostasis, the integrin GPIIb/IIIa (αIIbβ3, CD41/CD61) was destined to be an anti-thrombotic target. The subsequent successful development of intravenous ligand-mimetic inhibitors occurred during a time of limited understanding of integrin physiology. Although efficient inhibitors of ligand...